An increased consumption of fish and seafood are associated with various health benefits. Many of the health benefits have been attributed to the omega-3 fatty acids, eicosapentaenoic acid (EPA, 20:5n-3) and docosahexaenoic acid (DHA, 22:6n-3) that are found in fish.
My research is can be divided into three major themes:
1. The development of high throughput methods for fatty acid research and clinical assessment.
2. The metabolism of polyunsaturated fatty acids, particularly the impact of gender and sex on DHA (22:6n-3).
3. Dietary strategies to increase the intakes of omega-3 polyunsaturated fatty acids and the impact of dietary interventions on health.
1. Patterson, A.C. and Stark, K.D. Direct determinations of the fatty acid composition of daily dietary intakes incorporating nutraceuticals and functional food strategies to increase n-3 highly unsaturated fatty acids. Journal of the American College of Nutrition (in press, accepted April 23, 2008).
2. Stark, K.D. Analytical implications of routine clinical testing for omega-3 fatty acid biomarkers. Lipid Technology, 2008, 20, 177-179.
3. Armstrong, J.M., Metherel, A.H., and Stark, K.D. Direct microwave transesterification of fingertip prick blood samples for fatty acid determinations. Lipids, 2008, 43, 187-196.
4. Stark, K.D. The percentage of n-3 highly unsaturated fatty acids (HUFA) in total HUFA as a biomarker for omega-3 fatty acid status. Lipids, 2008, 43, 45-53.
5. Stark, K.D., Lim, S.Y. and Salem, N., Jr. Artificial rearing with docosahexaenoic acid and n-6 docosapentaenoic acid alters rat tissue fatty acid composition. Journal of Lipid Research, 2007, 48, 2471-2477.